Quantitative magnetic resonance imaging on hybrid magnetic resonance linear accelerators: Perspective on technical and clinical validation

Physics and Imaging in Radiation Oncology

Marcel Nachbar¹  Matthias Ege²  Simon Boeke²  Daniela Thorwarth³  Daniel Zips³  David Mönnich³  Cihan Gani³ 

[1] Corresponding author at: Section for Biomedical Physics, Department of Radiation Oncology, University Hospital Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.;German Cancer Consortium (DKTK), Partner Site Tübingen, and German Cancer Research Center (DKFZ), Heidelberg, Germany;Section for Biomedical Physics, Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany;

关键词: MR-Linac;    MR-guided radiotherapy;    Quantitative MRI;    Diffusion-weighted MRI;   

DOI  :  

来源: DOAJ

【 摘 要 】

Many preclinical and clinical observations support that functional magnetic resonance imaging (MRI), such as diffusion weighted (DW) and dynamic contrast enhanced (DCE) MRI, might have a predictive value for radiotherapy. The aim of this review was to assess the current status of quantitative MRI on hybrid MR-Linacs. In a literature research, four publications were identified, investigating technical feasibility, accuracy, repeatability and reproducibility of DW and DCE-MRI in phantoms and first patients. Accuracy and short term repeatability was < 5% for DW-MRI in current MR-Linac systems. Consequently, quantitative imaging providing accurate and reproducible functional information seems possible in MR-Linacs.

【 授权许可】

Unknown