Lepromatous leprosy and human immunodeficiency virus co-infection associated with phenomenon of Lucio versus immune reconstitution inflammatory syndrome

Infectio

关键词: Leprosy;    Lucio's phenomenon;    Immune reconstitution inflammatory syndrome (IRIS);    Human immunodeficiency virus (HIV);    Highly active antiretroviral therapy (HAART);    Mycobacterium leprae;    Mycobacterium lepromatosis;   

DOI  :  10.1016/j.infect.2015.10.011

来源: DOAJ

【 摘 要 】

Abstract: Diffuse lepromatous leprosy (DLL) is a severe clinical outcome of lepromatous leprosy (LL). The aetiologic cause is believed to be different from Mycobacterium leprae. A new species, Mycobacterium lepromatosis, was identified from a group of Mexican patients with DLL, and severe leprosy reactional state type 3 (Lucio's phenomenon). However, a total sequencing of its genome is necessary to prove the existence of this new species. This is a report on a non-typical Colombian case of leprosy - HIV coinfection, associated with an immune reconstitution inflammatory syndrome clinically compatible with a leprosy reaction type 3 or Lucio's phenomenon.

【 授权许可】

Unknown