Graphene derivatives and organic polymers nanocomposites for tissue engineering and regenerative medicine

Memoirs of the Scientific Sections of the Romanian Academy

Ecaterina Andronescu¹  Anton Ficai¹  Cristina Chircov¹ 

[1] Department of Science and Engineering of Oxide Materials and Nanomaterials Faculty of Applied Chemistry and Materials Science University Politehnica of Bucharest, Romania;

关键词: graphene;    graphene oxide;    polymer nanocomposites;    tissue engineering;   

DOI  :  

来源: DOAJ

【 摘 要 】

Carbon-based materials, especially graphene and graphene derivatives, have proved their wide applicability in various fields. In the biomedical arena, graphene is regarded as the most important technological breakthrough, due to its unique and advantageous properties. In this regard, it allows for surface functionalization that further provides the means for covalently and non-covalently conjugating various molecules and macromolecules. However, studies on its biocompatibility and biodegradability properties are somewhat contradictory, so that its combination with other materials is required. Organic polymers are an example of such materials, that have further enhanced the applicability of graphene-based materials in the biomedical field. Specifically, tissue engineering and regenerative medicine have benefitted from these advancements. Accordingly, the aim of this paper is to provide an overview of the main graphene functionalization strategies and graphene-polymer nanocomposites synthesis methods, as well as their most recent applications in nerve, bone, cartilage, and muscle tissue engineering and regeneration.

【 授权许可】

Unknown