Review: Vaccines and Vaccination against Lumpy Skin Disease

Vaccines

Charles Euloge Lamien¹  Janika Wolff²  Bernd Hoffmann²  Carola Sauter-Louis³  Franz J. Conraths³  Hannes Bergmann³  Anna Fahrion⁴  Eeva Tuppurainen⁴  Frank Busch⁴  Klaas Dietze⁴  Sascha Knauf⁴  Daniel Beltran-Alcrudo⁵  Kris De Clercq⁶ 

[1] FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications, International Atomic Energy Agency (IAEA), Friedenstrasse 1, A-2444 Seibersdorf, Austria;Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, D-17493 Greifswald-Insel Riems, Germany;Institute of Epidemiology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, D-17493 Greifswald-Insel Riems, Germany;Institute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, D-17493 Greifswald-Insel Riems, Germany;Regional Office for Europe and Central Asia, Food and Agriculture Organization, 20 Kalman Imre utca, H-1054 Budapest, Hungary;Unit of Exotic and Particular Diseases, Scientific Directorate Infectious Diseases in Animals, Sciensano, Groeselenberg 99, B-1180 Brussels, Belgium;

关键词: capripoxvirus;    lumpy skin disease;    cattle;    LSD;    immunization;    vaccination;   

DOI  :  10.3390/vaccines9101136

来源: DOAJ

【 摘 要 】

The geographical distribution of lumpy skin disease (LSD), an economically important cattle disease caused by a capripoxvirus, has reached an unprecedented extent. Vaccination is the only way to prevent the spread of the infection in endemic and newly affected regions. Yet, in the event of an outbreak, selection of the best vaccine is a major challenge for veterinary authorities and farmers. Decision makers need sound scientific information to support their decisions and subsequent actions. The available vaccine products vary in terms of quality, efficacy, safety, side effects, and price. The pros and cons of different types of live attenuated and inactivated vaccines, vaccination strategies, and associated risks are discussed. Seroconversion, which typically follows vaccination, places specific demands on the tools and methods used to evaluate the effectiveness of the LSD vaccination campaigns in the field. We aimed to give a comprehensive update on available vaccines and vaccination against LSD, to better prepare affected and at-risk countries to control LSD and ensure the safe trade of cattle.

【 授权许可】

Unknown