Synthesis, characterization, and biological activity of a new class of dialkylphosphorylhydrazone derivatives of isatin

Química Nova

Marcela Jacques de Lemos¹  Sonia Regina de Souza¹  Vinícius Tomaz Gonçalves¹  João Batista Neves DaCosta¹  Marco Andre Alves de Souza¹  Victor Marcos Rumjanek¹  Letícia Silotti Zampirolli¹ 

[1] Universidade Federal Rural do Rio de Janeiro;

关键词: dialkylphosphorylhydrazones;    isatins;    biological activity;   

DOI  :  10.5935/0100-4042.20140162

来源: DOAJ

【 摘 要 】

Sixteen dialkylphosphorylhydrazones were synthesized by condensation of phosphorylhydrazines with substituted isatins. Products were characterized by FTIR, ¹H-NMR, 13C-NMR, and 31P-NMR. Fungicidal activities of these compounds against Rhizoctonia solani and Fusarium oxysporum were also evaluated. Some compounds inhibited the growth of Rhizoctonia solani and Fusarium oxysporum by 43% and 51%, respectively. These compounds exhibited no effects on germination of lettuce seeds (Lactuca sativa L).

【 授权许可】

Unknown