Management of Pheochromocytomas and Paragangliomas: A Case-Based Review of Clinical Aspects and Perspectives

Journal of Clinical Medicine

Jacek Rutkowski¹  Adrian Perdyan²  Bartosz Kamil Sobocki³  Olga Szot³ 

[1] Department of Oncology and Radiotherapy, Medical University of Gdansk, 80-214 Gdansk, Poland;International Research Agenda 3P Medicine Laboratory, Medical University of Gdansk, 80-210 Gdansk, Poland;Student Scientific Circle of Oncology and Radiotherapy, Medical University of Gdansk, 80-214 Gdansk, Poland;

关键词: pheochromocytoma;    paraganglioma;    neuroendocrine tumors;    radiology;    nuclear medicine;   

DOI  :  10.3390/jcm11092591

来源: DOAJ

【 摘 要 】

Paraganglioma and pheochromocytoma are rare medical conditions. Thus, there are still a small number of studies, clinical trials, and evidence-based data in this field. This makes clinical decisions more difficult. In this study, we present a case report enriched with a short review of available essential clinical data, indicating the need for constant metoxycatecholamine level observation and a proper diagnostic imaging approach, especially in terms of ongoing pandemics. Our research also provides a summary of the molecular background of these diseases, indicating their future role in clinical management. We analyzed the ClinicalTrials.gov dataset in order to show future perspectives. In this paper, the use of the PET-CT before MRI or CT is proposed in specific cases during diagnosis processes contrary to the guidelines. PET-CT may be as effective as standard procedures and may provide a faster diagnosis, which is important in periods with more difficult access to health care, such as during the COVID-19 pandemic.

【 授权许可】

Unknown