Evaluation of Hepatic, Renal and Cardiac Diagnostic Markers in Patients With Severe COVID-19

Acta Medica Iranica

Sara Mobarak¹  Saeed Jelvay²  Asma Mohammadi³  Atefeh Zahedi⁴  Fatemeh Maghsoudi⁵  Esmat Radmanesh⁶  Mohammad Hosein Assareh Zadegan Dezfuli⁷  Ali Reza Balizadeh Karami⁷ 

[1] Clinical Research Development Unit, Taleghani Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran.AND Department of Infectious Disease, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran;Clinical Research Development Unit, Valiasr Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran.AND Department of Health Information Technology, Abadan University of Medical Sciences, Abadan, Iran;Clinical Research Development Unit, Valiasr Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran;Department of Public Health, Asadabad School of Medical Sciences, Asadabad, Iran;Department of Public Health, School of Health, Abadan University of Medical Sciences, Abadan, Iran;Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran. ANDDepartment of Physiology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran;Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran;

关键词: Diagnostic markers;    Coronavirus disease 2019 (COVID-19);    Abadan;   

DOI  :  10.18502/acta.v59i11.7778

来源: DOAJ

【 摘 要 】

SARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) was first known in Wuhan, China, in December 2019. The aim of this study was to evaluate the level of common hepatic, renal, and cardiac diagnostic markers in hospitals in patients with severe COVID 19. In this study, 259 patients with symptoms of severe COVID-19 and a positive RT-PCR assay of nasopharyngeal samples were enrolled. Inclusion criteria are positive for COVID-19 patients at the diagnosis of an infectious disease physician. Diagnostic markers of liver, kidney, and heart were evaluated by age and gender. In this study, 48.3% of patients severe with COVID-19 were male, and 51.7% were female. The mean of markers such as LDH, Direct Bilirubin, SGOT, SGPT, D-dimer was higher than normal, which was observed in men more than women. The mean of CK-MB also was higher than normal, which was observed in women more than men. The highest mean of markers was seen in the older ages. The mean of BUN was observed in the age range of 55-64 years and above 65 years above normal. But the mean of CPK, creatinine, potassium and alkaline phosphatase were normal. The results of the present study showed an increase in the level of some of the most important diagnostic markers of hepatic, renal, and cardiac in patients with COVID 19. This increase was greater in some markers, including SGOT, SGPT, Direct bilirubin, LDH, D-dimer, in men than in women, and more in older patients.

【 授权许可】

Unknown