Multisite quantitative ultrasound: It′s comparison with dual energy X-ray absorptiometry in the diagnosis of osteoporosis

Journal of Orthopaedics and Allied Sciences

关键词: Dual energy X-ray absorptiometry;    osteoporosis;    quantitative ultrasound;   

DOI  :  10.4103/2319-2585.145598

来源: DOAJ

【 摘 要 】

Background: The aim of the study was to establish the correlation between dual-energy X-ray absorptiometry (DXA) and quantitative ultrasound (QUS) and to assess the ability of QUS as a screening tool for osteoporosis. Materials and Methods: The study was conducted on 101 healthy women, aged 20-65 years. All the women underwent QUS of radius and tibia using Omnisense bone densitometer and DXA screening for measurement of bone mineral density (BMD) at lumbar spine, total hip, and femoral neck. Results: Significant correlations were observed between speed of sound (SOS) and BMD measurement in all age groups, with the closest association. In the age group of 20-40 years, BMD of femoral neck showed the closed association with SOS radius (0.858, P < 0.01) and SOS tibia (0.860, P < 0.01). Similar trend was observed in the other two age groups as well. All subjects in the premenopausal (41-50 years) and postmenopausal (51-65 years) age group were correctly detected for osteopenia/bone density below the expected range for age and osteoporosis by QUS, as against the diagnosis made by DXA. Post hoc test revealed a significant difference in the BMD of femoral neck, lumbar spine, and SOS radius and tibia in young and postmenopausal females. Conclusion: QUS is a sensitive screening tool to detect changes in the bone mass and risk of osteoporosis.

【 授权许可】

Unknown