Mathematical evaluation of hemolysis in a channel centrifugal blood pump

Vestnik Transplantologii i Iskusstvennyh Organov

A. S. Buchnev¹  A. P. Kuleshov²  G. P. Itkin²  A. A. Drobyshev² 

[1] Moscow Institute of Physics and Technology;Shumakov National Medical Research Center of Transplantology and Artificial Organs;

关键词: 3d modeling;    mechanical circulatory support;    channel centrifugal blood pump;    shear stress;    exposure time;    hemolysis index;   

DOI  :  10.15825/1995-1191-2020-3-79-85

来源: DOAJ

【 摘 要 】

The objective of this work is to conduct research on a mathematical model to assess hemolytic characteristics in a channel centrifugal blood pump developed by us with 2000–3400 rpm impeller speed range and 100–250 mmHg pressure drop in different parts of the pump flow path. Hemolysis index was measured at 1 to 10 L/min flow rate. The result was an estimate of the average magnitude of the shear stress (SS), taking into account the distribution in the pump, which ranged from 40 to 60 Pa. The most critical areas of the pump in terms of blood injury were evaluated. The maximum SSs were determined: 456 Pa in the impeller wheel zone and 533.3 Pa in the adjacent area of the body, with an exposure time of 0.0115 s and 0.0821 s respectively. In these zones, maximum hemolysis index values were 0.0420 and 0.0744 respectively. Based on the data obtained, these zones were optimized in terms of minimizing hemolysis.

【 授权许可】

Unknown