A green approach for the synthesis of 2-substituted benzoxazoles and benzothiazoles via coupling/cyclization reactions

Heliyon

Cong Tien Nguyen¹  Trinh Hao Nguyen¹  Dung Duc Pham²  Hai Truong Nguyen²  Phuong Hoang Tran³ 

[1] Vietnam National University, Ho Chi Minh City, Viet Nam;Department of Organic Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, Viet Nam;Faculty of Chemistry, Ho Chi Minh City University of Education, Viet Nam;

关键词: Magnetic ionic liquids;    Benzoxazoles;    Benzothiazoles;    Green method;    Sonication;    Solvent-free condition;   

DOI  :  

来源: DOAJ

【 摘 要 】

We have developed the green method for the synthesis of benzoxazoles and benzothiazoles with moderate to good yields using imidazolium chlorozincate (II) ionic liquid supported into Fe3O4 nanoparticles (LAIL@MNP) under solvent-free sonication. The reaction was performed under mild conditions and only produced water as a sole byproduct. The reactions under solvent-free sonication showed advantages of faster reaction rate (30 min) and high yields of the products (up to 90%). Moreover, the LAIL@MNP material was easily separated from the reaction mixture and can be recycled for five consecutive runs with a slight decrease in its catalytic performance (from 82 to 73%).

【 授权许可】

Unknown