Medicinal Potential of Garcinia Species and Their Compounds

Molecules

WanderFernando de Oliveira Filiú¹  Danielle Bogo²  PriscilaAiko Hiane²  LidianiFigueiredo Santana²  PauloRoberto Haidamus de Oliveira Bastos²  Ritade Cássia Avellaneda Guimarães²  Karinede Cássia Freitas²  BrunaLarissa Spontoni do Espirito Santo²  Felipede Oliveira de Araújo³  WilsonHino Kato Junior⁴  Patríciade Oliveira Figueiredo⁵  Arnildo Pott⁶  Marcel Arakaki Asato⁷ 

[1]Faculty of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil

[2]Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil

[3]Graduate of Electrical Engineering, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil

[4]Graduate of Pharmaceutical Sciences, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil

[5]Laboratory PRONABio (Bioactive Natural Products)-Chemistry Institute, Federal University of Mato Grosso do Sul-UFMS, 79074-460 Campo Grande, Brazil

[6]Laboratory of Botany, Institute of Biosciences, Federal University of Mato Grosso do Sul, 79070-900 Campo Grande, Brazil

[7]Medical School, Federal University of Mato Grosso do Sul, 79070-900 Campo Grande, Brazil

关键词: Clusiaceae;    phytochemical compounds;    therapeutic effects;   

DOI  :  10.3390/molecules25194513

来源: DOAJ

【 摘 要 】

Garcinia is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New Caledonia, Polynesia, and Brazil. Garcinia plants contain a broad range of biologically active metabolites which, in the last few decades, have received considerable attention due to the chemical compositions of their extracts, with compounds which have been shown to have beneficial effects in several diseases. Our work had the objective of reviewing the benefits of five Garcinia species (G. brasiliensis, G. gardneriana, G. pedunculata, G. cambogia, and G. mangstana). These species provide a rich natural source of bioactive compounds with relevant therapeutic properties and anti-inflammatory effects, such as for the treatment of skin disorders, wounds, pain, and infections, having demonstrated antinociceptive, antioxidant, antitumoral, antifungal, anticancer, antihistaminic, antiulcerogenic, antimicrobial, antiviral, vasodilator, hypolipidemic, hepatoprotective, nephroprotective, and cardioprotective properties. This demonstrates the relevance of the genus as a rich source of compounds with valuable therapeutic properties, with potential use in the prevention and treatment of nontransmissible chronic diseases.

【 授权许可】

Unknown