Metagenomic Analysis of the Effects of Lactiplantibacillus plantarum and Fructooligosaccharides (FOS) on the Fecal Microbiota Structure in Mice

Foods

Weiling Guo¹  Hao Zhang¹  Jianxin Zhao¹  Bingyong Mao¹  Xin Tang¹  Shumao Cui¹  Cailing Chen¹ 

[1] State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China;

关键词: Lactiplantibacillus plantarum;    fructooligosaccharide;    short-chain fatty acids;    intestinal microbiota;   

DOI  :  10.3390/foods11091187

来源: DOAJ

【 摘 要 】

Understanding the association between food composition and intestinal microbiota in the context of individual health is a critical problem in personalized nutrition. The objective of the present research was to elucidate the influence of Lactiplantibacillus plantarum ST-III and fructooligosaccharides (FOS) on the intestinal microbiota structure. We found that L. plantarum ST-III and FOS interventions remarkably enhanced the levels of cecal short-chain fatty acids (SCFAs), especially acetic, butyric, and valeric acids. Moreover, L. plantarum ST-III and/or FOS intervention obviously altered the intestinal microbiota structure. At the genus level, L. plantarum ST-III and/or FOS intervention remarkably elevated the proportion of Sutterella, Pediococcus, Proteus, Parabacteroides, Prevotella and Desulfovibrio. Correlation analysis further uncovered that the specific compositional features of intestinal microbiota were strongly related to the concentration of cecal SCFAs. Our results offered scientific evidence to understanding the association between food composition and intestinal microbiota.

【 授权许可】

Unknown