Wearable Biosensors: An Alternative and Practical Approach in Healthcare and Disease Monitoring

Molecules

Mihaela Badea¹  Atul Sharma²  Swapnil Tiwari³  JeanLouis Marty⁴ 

[1] Fundamental, Prophylactic and Clinical Specialties Department, Faculty of Medicine, Transilvania University of Brasov, 500036 Brasov, Romania;School of Chemistry, Monash University, Clayton, Melbourne, VIC 3800, Australia;School of Studies in Chemistry, Pt Ravishankar Shukla University, Raipur, CG 492010, India;University of Perpignan via Domitia, 52 Avenue Paul Alduy, CEDEX 9, 66860 Perpignan, France;

关键词: wearable biosensor;    healthcare monitoring;    biomarkers;    biological fluids;    physiological conditions;   

DOI  :  10.3390/molecules26030748

来源: DOAJ

【 摘 要 】

With the increasing prevalence of growing population, aging and chronic diseases continuously rising healthcare costs, the healthcare system is undergoing a vital transformation from the traditional hospital-centered system to an individual-centered system. Since the 20th century, wearable sensors are becoming widespread in healthcare and biomedical monitoring systems, empowering continuous measurement of critical biomarkers for monitoring of the diseased condition and health, medical diagnostics and evaluation in biological fluids like saliva, blood, and sweat. Over the past few decades, the developments have been focused on electrochemical and optical biosensors, along with advances with the non-invasive monitoring of biomarkers, bacteria and hormones, etc. Wearable devices have evolved gradually with a mix of multiplexed biosensing, microfluidic sampling and transport systems integrated with flexible materials and body attachments for improved wearability and simplicity. These wearables hold promise and are capable of a higher understanding of the correlations between analyte concentrations within the blood or non-invasive biofluids and feedback to the patient, which is significantly important in timely diagnosis, treatment, and control of medical conditions. However, cohort validation studies and performance evaluation of wearable biosensors are needed to underpin their clinical acceptance. In the present review, we discuss the importance, features, types of wearables, challenges and applications of wearable devices for biological fluids for the prevention of diseased conditions and real-time monitoring of human health. Herein, we summarize the various wearable devices that are developed for healthcare monitoring and their future potential has been discussed in detail.

【 授权许可】

Unknown