Association between atrial fibrillation, frailty, and geriatric syndromes in the late elderly in a south Belgian outpatient and inpatient setting

American Heart Journal Plus

Smarandita Macovei¹  Antonio Sorgente²  Thibauld Preumont³  Gianbattista Chierchia⁴  Christophe de Terwangne⁵  Carlo de Asmundis⁶  Antoine de Meester⁷  Pierre Hanotier⁷ 

[1] Corresponding author at: Department of Geriatric Medicine, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200 Bruxelles, Belgium.;Department of Geriatric Medicine, Cliniques Universitaires Saint-Luc – Université Catholique de Louvain, 1200 Brussels, Belgium;Department of Cardiology and Rythmology, EpiCURA, 7301 Hornu, Belgium;Department of Geriatric Medicine, EpiCURA, 7301 Hornu, Belgium;Department of Geriatric Medicine, Hopital de Jolimont Groupe, 7100 La Louvière, Belgium;Department of Internal Medicine, Hopital de Jolimont Groupe, 7100 La Louvière, Belgium;Heart and Rhythm Management Center, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, 1090 Brussels, Belgium;

关键词: Frailty;    Atrial fibrillation;    Clinical frailty scale;    Elderly;    Rockwood;    Geriatric syndromes;   

DOI  :  

来源: DOAJ

【 摘 要 】

Study objective: This study aims to analyze the relationship between AF, frailty, and geriatric syndromes in elderly patients in an outpatient and inpatient setting in a South Belgian hospital. Participants, design and setting: This is a single center case-control retrospective study including 207 patients enrolled from an outpatient and inpatient setting of the Department of Geriatrics, Jolimont Hospital Group. Frailty was assessed using a complete geriatric assessment and Rockwoods Clinical Frailty Scale. Results: AF was strongly associated with age, cardiovascular history, congestive heart failure, as well as with multiple geriatric syndromes such as vascular dementia, malnutrition, functional decline in Activities of Daily Living, mobility impairment and chronic ulcerous disease. Furthermore, there was a tight relationship between AF and Rockwoods' frailty phenotypes. This association was maintained throughout multivariable modelling including age (OR 1.06, IC 1.03–1.14, p = 0.042), sex (OR 2.30, IC 1.11–4.84, p = 0.026), congestive heart failure (OR 3.70, IC 1.77–7.91, p < 0.001) and a CFS more than 4 (OR 2.68, IC 1.18–6.43, p = 0.021). Conclusion: A deeper understanding of associations between atrial fibrillation and geriatric syndromes and frailty could give new patient management perspectives beyond pharmaceutical or interventional treatment.

【 授权许可】

Unknown