Invasive Hormographiella aspergillata infection in patients with acute myeloid leukemia: Report of two cases successfully treated and review of the literature

Medical Mycology Case Reports

Jean Yannis Perentes¹  Pierre-Yves Bochud²  Olivier Spertini³  Sabina Berezowska⁴  Catherine Beigelman-Aubry⁵  Jonathan Tschopp⁶  Frederic Lamoth⁶  Alban Lovis⁷ 

[1] Corresponding author.;Department of Hematology, Lausanne University Hospital and University of Lausanne, 1011, Lausanne, Switzerland;Department of Pulmonology, Lausanne University Hospital and University of Lausanne, 1011, Lausanne, Switzerland;Department of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, 1011, Lausanne, Switzerland;Department of Thoracic Surgery, Lausanne University Hospital and University of Lausanne, 1011, Lausanne, Switzerland;Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, 1011, Lausanne, Switzerland;Institute of Pathology, Lausanne University Hospital and University of Lausanne, 1011, Lausanne, Switzerland;

关键词: Coprinopsis cinerea;    Hormographiella aspergillata;    Voriconazole;    Amphotericin B;    Fungal PCR;   

DOI  :  

来源: DOAJ

【 摘 要 】

Hormographiella aspergillata is a rare cause of invasive mold infection, mostly described in patients with hematological malignancies. We describe two cases of invasive H. aspergillata infections in patients with acute myeloid leukemia, successfully managed with complete surgical resection of the lesions and antifungal therapy of voriconazole alone or liposomal amphotericin B, followed by voriconazole, highlighting the key role of a multidisciplinary approach for the treatment of this rare and severe invasive mold infection.

【 授权许可】

Unknown