DRESS Syndrome: An Unusual Side Effect

Journal of Clinical and Diagnostic Research

Kapil Bhalla¹  Deepak Nehra²  Ashish Gupta²  Sanjiv Nanda³  Shuchi Mehra⁴ 

[1] Associate Professor, Department of Paediatrics, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.;Intern, Department of Paediatrics, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.;Senior Professor, Department of Paediatrics, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.;Senior Resident, Department of Microbiology, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.;

关键词: anti seizure drugs;    drug reaction;    eosinophilia;    drug hypersensitivity;   

DOI  :  10.7860/JCDR/2019/40069.12584

来源: DOAJ

【 摘 要 】

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is often an overlooked entity manifesting as fatal hypersensitivity response associated with use of aromatic anti-epileptic drugs. This case report shows a case of a nine-year-old male child presenting with DRESS syndrome associated with the use of oral carbamazepine. The patient presented with high grade fever, rashes in exposed areas of face and all extremities not involving palms, soles, or oral mucosa, periorbital oedema, and cervical lymphadenopathy. Patient was managed with oral prednisolone 1 mg/kg/day. Later the drug was changed to oral levetiracetam. Clinicians should always consider the possibility of DRESS syndrome with the use of anti-epileptic drugs.

【 授权许可】

Unknown