Prevalence of Sarcopenia and Its Association With Diabetes: A Meta-Analysis of Community-Dwelling Asian Population

Frontiers in Medicine

Min Cheol Chang¹  Seung Min Chung²  Jun Sung Moon² 

[1] Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, South Korea;Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeungnam University, Daegu, South Korea;

关键词: diabetes mellitus;    type 2;    geriatrics;    sarcopenia;    prevalence;    meta-analysis;   

DOI  :  10.3389/fmed.2021.681232

来源: DOAJ

【 摘 要 】

Purpose: Sarcopenia is a major disease affecting mortality and quality of life in the elderly population. We performed a meta-analysis of studies on the community-dwelling population to investigate the prevalence of sarcopenia and its association with diabetes.Methods: Databases were searched for studies published up to February 3, 2021, reporting the prevalence of sarcopenia in patients with and without diabetes. Data extraction and quality assessment were performed according to the Newcastle-Ottawa scale.Results: Six articles were included in the systematic review. All the patients were Asian, aged ≥60 years (women 53.4%), and the diabetic and non-diabetic population was 1,537 and 5,485, respectively. In all six studies, the Asian Working Group for Sarcopenia criteria were used to diagnose sarcopenia. The prevalence of sarcopenia was 15.9% in diabetics and 10.8% in non-diabetics. Diabetics showed a significantly higher risk of sarcopenia than non-diabetics (pooled OR = 1.518, 95% CI = 1.110 to 2.076, Z-value = 2.611, p = 0.009).Conclusion: Among the Asian community-dwelling geriatric population, the prevalence of sarcopenia was significantly higher in diabetics than in non-diabetics. These results suggest that strategies for the management of sarcopenia are required in Asian elderly patients, especially with diabetes.

【 授权许可】

Unknown