An electrochemical sensor based on copper nanowires-PDDA modified glassy carbon electrode for amperometric detection of cysteine in alkaline medium

Results in Chemistry

Jianyu Qiao¹  Shijun Shao¹  Cong Tang²  Zhixing Zeng² 

[1] University of Chinese Academy of Sciences, Beijing 100049, China;CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China;

关键词: Copper nanowires;    Chemically modified electrode;    Electrochemical sensor;    Cysteine;    Chronoamperometry;   

DOI  :  

来源: DOAJ

【 摘 要 】

The development of highly efficient and stable electrocatalysts for their application in electrochemical detection is desirable. Herein, a new copper nanowires (CuNWs) modified electrode was fabricated by coating poly(dimethyl diallyl ammonium chloride) (PDDA) stabilized CuNWs composite onto the the glassy carbon electrode (GCE), and used for electro-catalyze and determination of cysteine (CySH). The morphology, structure, and surface property of fabricated CuNWs were tested using SEM, XRD, and XPS, separately. Electrocatalytic behavior of the modified electrode (CuNWs-PDDA/GCE) for CySH oxidation in alkaline medium was researched by cyclic voltammetry (CV) and chronoamperometry (CA) thoroughly, displaying excellent electrocatalytic oxidation activity and sensing ability towards CySH with a rapid and sensitive anodic current response at low oxidation potential. In the amperometric detection of CySH, the as-prepared electrode displayed a significantly wide linear range from 2 μM to 260 μM and a detection limit of 0.19 μM with a sensitivity of 1.430 μAμM−1cm−2. The proposed CySH sensor exhibited good reproducibility, stability, and anti-interference ability, and has been used to detect CySH in human plasma samples successfully with good applicability.

【 授权许可】

Unknown