Factors associated with interruption of treatment among pulmonary tuberculosis patients in Plateau State, Nigeria, 2011

The Pan African Medical Journal

Okey Nwanyanwu¹  Ibrahim Dalhatu¹  Idris Suleiman Hadejia²  Peter Nsubuga³  Moses Obiemen Akhimien⁴  Ndadilnasiya Endie Waziri⁴  Luka Mangveep Ibrahim⁴  Patrick Nguku⁴  Raymond Dankoli⁴  Akin Oyemakinde⁴  Samuel Ogiri⁵ 

[1] Centers for Disease Control and Prevention, Nigeria Country Office, Abuja Nigeria;Department of Community Medicine, Ahmadu Bello University, Zaria, Nigeria;Global Public Health Solution, Decatur GA USA;Nigeria Field Epidemiology and Laboratory Training Program, Nigeria;World Health Organization, Nigeria;

关键词: interruption;    treatment;    tuberculosis;    nigeria;   

DOI  :  10.11604/pamj.2014.17.78.3464

来源: DOAJ

【 摘 要 】

INTRODUCTION: Nigeria has one of the highest tuberculosis (TB) burdens in the world with estimated incidence of 133 per 100,000 populations. Multi-drug resistant TB (MDR-TB) is an emerging threat of the TB control in Nigeria caused mainly by incomplete treatment. This study explored factors that affect adherence to treatment among patients undergoing direct observation of TB treatment in Plateau state, Nigeria. METHODS: Between June and July 2011, we reviewed medical records and interviewed randomly selected pulmonary TB patients in their eighth month of treatment. Information on patients' clinical, socio-demographic and behavioral characteristics was collected using checklist and structured questionnaire for knowledge of treatment duration and reasons for interruption of treatment. We conducted focus group discussions with patients about barriers to treatment adherence. Data were analyzed with Epi Info software. RESULTS: Of 378 records reviewed, 229 (61%) patients were male; mean age 37.6 ,13.5 years and 71 (19%) interrupted their treatment. Interruption of treatment was associated with living5 km from TB treatment site (AOR: 11.3; CI 95%: 5.7-22.2), lack of knowledge of duration of treatment (AOR: 6.1; CI 95%: 2.8-13.2) and cigarette smoking (AOR: 3.4; CI 95%: 1.5- 8.0). Major reasons for the interruption were lack of transport fare (40%) and feeling well (25%). Focused group discussions revealed unfriendly attitudes of health care workers as barriers to adherence to treatment. ONCLUSION: This study revealed knowledge of the patients on the duration of treatment, distance and health workers attitude as the major determinants of adherent to TB treatment. Training for health care workers on patient education was conducted during routine supportive supervision.

【 授权许可】

Unknown