National predictors of influenza vaccine uptake in pregnancy: the FluMum prospective cohort study, Australia, 2012–2015

Australian and New Zealand Journal of Public Health

Kerry‐Ann F. O'Grady¹  Mark D. Chatfield²  Ross M. Andrews²  Paula Binks²  Lisa McHugh²  Michael J. Binks²  Kirsten P. Perrett³  Nicholas Wood⁴  Peter C. Richmond⁵  Terry Nolan⁶  Stephen B. Lambert⁷  Helen S. Marshall⁸ 

[1] Australian Centre for Health Services Innovation, Centre for Healthcare Transformation Queensland University of Technology;Menzies School of Health Research Charles Darwin University Northern Territory;Murdoch Children's Research Institute, Royal Children's Hospital and Department of Paediatrics The University of Melbourne Victoria;National Centre for Immunisation Research and Surveillance (NCIRS) and The Faculty of Medicine and Health University of Sydney New South Wales;Perth Children's Hospital, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute and Division of Paediatrics University of Western Australia New South Wales;Peter Doherty Institute for Infection and Immunity The University of Melbourne, and Murdoch Children's Research Institute;Research School of Population Health Australian National University Australian Capital Territory;Women's and Children's Health Network and Robinson Research Institute and Adelaide Medical School The University of Adelaide South Australia;

关键词: influenza;    vaccination;    pregnancy;    predictors;   

DOI  :  10.1111/1753-6405.13130

来源: DOAJ

【 摘 要 】

Abstract Objective: Ascertain predictors of inactivated influenza vaccine (IIV) uptake in pregnancy in mother–infant pairs from six Australian sites over four consecutive influenza seasons (2012–2015). Methods: Prospective observational cohort study calculating proportions of unvaccinated and vaccinated pregnancies. Multivariable logistic regression calculating adjusted odds ratios (aOR) and 95% confidence intervals (95%CI) to determine demographic, pregnancy and birth characteristics as predictors of IIV uptake in pregnancy. Results: Uptake of IIV was 36% (n=3,651/9,878) with only 3–4% during the first trimester. Validation of IIV receipt was obtained for 77% of vaccinated participants. Predictors of IIV uptake in pregnancy were: healthcare provider recommendation to have IIV during pregnancy (aOR 7.04 [95%CI 5.83‐8.50]): GP (aOR 4.12 [95%CI 3.43‐4.98]), obstetrician (aOR 4.41 [95%CI 3.45‐5.64]), midwife (aOR 1.88 [95%CI 1.51‐2.36]); previous IIV within 12 months of their current pregnancy (aOR 2.87 [95%CI 2.36‐3.50]); and pertussis vaccination during the current pregnancy (aOR 4.88 [95%CI 4.08‐5.83]). Conclusions and implications for public health: Healthcare provider discussions with pregnant women about the risks associated with influenza infection during pregnancy and early infancy and evidence about the safety and effectiveness of IIV are required. Recommending and offering IIV in pregnancy needs to be included in these discussions to improve uptake.

【 授权许可】

Unknown