Weight Loss Through Bariatric Surgery in Men Presents Beneficial Effects on Sexual Function, Symptoms of Testosterone Deficiency, and Hormonal Profile

Sexual Medicine

Sérgio Ricardo Pioner, MD, MSc¹  Ernani Luis Rhoden, MD, PhD²  Luis Vinicius Bastos de Souza, MD²  Bruno Chao Lisot, MD³  Igor Pires Drachler, MD⁴  Felipe Pioner Machado, MD⁵  Graziele Halmenschlager, PhD⁶ 

[1] Corresponding Author: Felipe Pioner Machado, MD, Avenida Praia de Belas 2124, sala 905, Porto Alegre, Rio Grande do Sul 90110-000, Brazil. Tel: [phone];Urologist of Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil;Bariatric Surgeon of Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil;Centro Universitário CESUCA, Cachoeirinha, Brazil;Postgraduate in Health Sciences at Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil;Professor of Urology and Advisor of Postgraduate Studies Programs at Universidade, Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil;

关键词: Bariatric Surgery;    Weight Loss;    Sexual Function;    Erectile Function;    Testosterone;    Low T Symptoms;   

DOI  :  

来源: DOAJ

【 摘 要 】

Introduction: Male obesity has a negative correlation with plasma testosterone (T) levels and sexual function (SF). Aim: To evaluate the effect of weight loss through bariatric surgery (BS) on SF, low T symptoms, and hormonal profiles in obese men. Methods: Thirty-three men who underwent BS participated in this cohort study. Before surgery, all participants underwent clinical examinations, including anthropometric, lipid, glycemic, and hormonal evaluations. SF was evaluated using the International Index of Erectile Function (IIEF) questionnaire; low T symptoms were evaluated using the Aging Males’ Symptoms (AMS) and Androgen Deficiency in the Aging Male (ADAM) questionnaires. The participants were reevaluated 6 months post-surgery. Main outcome measures: Sex hormone profile, SF, and low T symptoms Results: After BS, a significant increase in mean total T (201 ± 111–548 ± 190 ng/dL, P < .001), free T (5.8 ± 2.8–9.3 ± 3.4 ng/dL, P < .001), bioavailable T (110.3 ± 57.8–198.6 ± 74.3 ng/dL, P < .001), and sexual hormone-binding globulin (19.8 ± 13.7–54.6 ± 23.2 nmol/L, P < .001) levels. There was a significant decrease in estradiol (64.6 ± 27.4–29.2 ± 20.0 [pg/mL], P < .001). SF significantly improved. The total IIEF score increased 5.2 points (62.3 ± 7.4–67.5 ± 7.4, P = .004), erectile function subdomain increased 2.4 points (25.7 ± 4.1–28.1 ± 3.9, P = .011), desire subdomain increased 1.0 points (8.3 ± 1.5–9.3 ± 1.6, P = .006), and intercourse satisfaction subdomain increased 1.2 points (11.4 ± 1.9–12.6 ± 1.8, P = .012). Post-surgery, a 44% reduction (P = .001) was observed in the positive ADAM questionnaire, and improvements in all domains of the AMS questionnaire were found (P < .001). Conclusion: Significant weight loss through BS improves erectile function, hormonal profile, and symptoms of T deficiency.Machado FP, Rhoden EL, Pioner SR, et al. Weight Loss Through Bariatric Surgery in Men Presents Beneficial Effects on Sexual Function, Symptoms of Testosterone Deficiency, and Hormonal Profile. Sex Med 2021;9:100400.

【 授权许可】

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