Comparing Diagnosis and Treatment of Pulmonary Hypertension Patients at a Pulmonary Hypertension Center versus Community Centers

Diseases

Kathleen Rottman-Pietrzak¹  Victoria Reams¹  Scott A. Helgeson²  Ahmed Abdelrahim²  John E. Moss²  Charles D. Burger²  Hollie Saunders²  Tonya K. Zeiger² 

[1] Department of Pharmacy Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA;Department of Pulmonary Medicine Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA;

关键词: pulmonary hypertension;    pulmonary hypertension center;    medication management;   

DOI  :  10.3390/diseases10010005

来源: DOAJ

【 摘 要 】

Once patients are diagnosed with pulmonary hypertension it is important to identify the correct diagnostic group as it will have implications on the disease state management. Pulmonary hypertension is increasingly diagnosed and treated in general medical practices; however, evidence-based guidelines recommend evaluation and treatment in pulmonary hypertension centers for accurate diagnosis and appropriate treatment recommendations. We conducted a retrospective cohort study of 509 random patients 18 years and older who were evaluated in our pulmonary hypertension clinic from January 2005 to December 2018. 68.4% (n = 348) had their diagnostic group clarified or changed. Pulmonary hypertension was deemed an incorrect diagnosis in 12.4% (n = 63). A total of 114 patients (22.4%) had been initiated on pulmonary hypertension specific treatment prior to presentation. Pulmonary hypertension specific medication was stopped in 57 (50.0%) cases. The estimated monthly saving of the stopped medication based on wholesale acquisition costs was USD 396,988.05–419,641.05, a monthly saving of USD 6964.70–7362.12 per patient. Evaluation outside of a pulmonary hypertension center may lead to misdiagnosis and inappropriate or inadequate treatment. Pulmonary arterial hypertension directed therapy improves median survival, but inappropriate therapy may cause harm; therefore, patients benefit from a specialized center with multiple resources to secure an accurate diagnosis and tailored treatment for their condition.

【 授权许可】

Unknown