Overview of Plasma and Platelet Transfusions in Critically Ill Children

Frontiers in Pediatrics

Oliver Karam¹  Stacie Kahn²  Madhuradhar Chegondi³  Marianne E. Nellis⁴ 

[1] Division of Pediatric Critical Care Medicine, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, United States;Division of Pediatric Critical Care Medicine, NewYork-Presbyterian, Morgan Stanley Children's Hospital, New York, NY, United States;Division of Pediatric Critical Care Medicine, Stead Family Children's Hospital- Carver College of Medicine, University of Iowa, Iowa, IA, United States;Pediatric Critical Care Medicine, NewYork-Presbyterian Hospital – Weill Cornell Medicine, New York, NY, United States;

关键词: platelet transfusion;    plasma;    critical ill children;    hemostasis;    hemorrhage;   

DOI  :  10.3389/fped.2020.601659

来源: DOAJ

【 摘 要 】

Critically ill children are a unique population who frequently receive plasma and platelet transfusions for both active bleeding and mitigation of bleeding risk. While these products are frequently administered, transfusion indications in this population remain unclear, and practice varies across institutions and providers. In this manuscript, we will outline the current evidence regarding plasma and platelet transfusions for hemostasis in the pediatric intensive care setting. For both products, we will describe the product composition, epidemiology, and product indications and discuss the potential risks and benefits involved with the transfusion. We will also discuss knowledge gaps and future areas of research.

【 授权许可】

Unknown