Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis

Clinical Endoscopy

Weon Jin Ko¹  Ji Hyun Song¹  Hak Su Kim¹  In Kyun Yoo¹  Hee Kyung Kim¹  Ga Won Song¹  Chang-Il Kwon¹  Joo Young Cho¹ 

[1] Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea;

关键词: Early esophageal cancer;    Concurrent chemoradiotherapy;    Endoscopic submucosal dissection;   

DOI  :  10.5946/ce.2018.176

来源: DOAJ

【 摘 要 】

Endoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can be difficult. Here, we present the preliminary results of endoscopic submucosal dissection followed by concurrent chemoradiotherapy for early esophageal cancer with a high risk of lymph node metastasis. From May 2006 to January 2014, six patients underwent concurrent chemoradiotherapy after endoscopic submucosal dissection with a median follow-up period of 63 months. No complications were encountered during concurrent chemoradiotherapy. Although local recurrence did not occur in all patients, two patients were diagnosed with metachronous cancer. Overall, the survival rate was 100%. Thus, endoscopic submucosal dissection followed by concurrent chemoradiotherapy may be a feasible treatment for early esophageal cancer in patients with a high risk of lymph node metastasis. Future prospective large-scale studies are warranted to confirm our results.

【 授权许可】

Unknown