Differentiation between suture recurrence and suture granuloma after pulmonary resection for lung cancer by diffusion-weighted magnetic resonance imaging or FDG-PET / CT

Translational Oncology

Shun Iwai¹  Yoshimichi Ueda²  Keiya Hirata³  Sohsuke Yamada⁴  Mariko Doai⁴  Munetaka Matoba⁵  Aika Yamagata⁵  Katsuo Usuda⁵  Yoshihito Iijima⁵  Nozomu Motono⁵  Hidetaka Uramoto⁶ 

[1] Corresponding author at: Department of Thoracic Surgery, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa, 920-0293, Japan.;Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293 Japan;Department of Pathophysiological and Experimental Pathology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293 Japan;Department of Radiology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293 Japan;Department of Thoracic Surgery, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293 Japan;MRI Center, Kanazawa Medical University Hospital, Uchinada, Ishikawa, 920-0293 Japan;

关键词: Diffusion-weighted magnetic resonance imaging (DWI);    Magnetic resonance imaging (MRI);    18-fluoro-2-deoxy-glucose positron emission tomography / computed tomography (FDG-PET/CT);    Lung cancer;    Suture recurrence;    Suture granuloma;   

DOI  :  

来源: DOAJ

【 摘 要 】

There has been no publication which supports the usefulness of DWI differentiating for suture recurrence and suture granuloma after resection for lung cancer. We presented efficacy of DWI or FDG-PET/CT for an assessment of suture lesions after resection for lung cancer. Thirteen suture recurrences and 15 suture granulomas were examined. There were 24 adenocarcinomas and 4 squamous cell carcinomas, and 26 partial resections and 2 segmentectomies. The period of time (907±907 days) between surgery and suture recurrence was not significantly longer than that (546±547 days) between surgery and suture granuloma. Diffusion detectability scores (a 5-point scale) of suture recurrences was significantly higher than that of suture granulomas. The ADC value (1.35±0.24 × 10−3mm2/sec) of suture recurrences was significantly lower than that (1.85±0.60 × 10−3mm2/sec) of suture granulomas. The SUVmax (6.1 ± 5.0) of suture recurrences was not significantly higher than that (4.2 ± 2.5) of suture granulmas. The sensitivity of 85% (11/13) with DWI was not significantly higher than 69% (9/13) with FDG-PET/CT for suture recurrences. The specificity of 73% (11/15) with DWI was not significantly higher than the 60% (9/15) with FDG-PET/CT for suture granulomas. The accuracy of 79% (22/28) with DWI was not significantly higher than that of 64% (18/28) with FDG-PET/CT for suture recurrences and granulomas. DWI can differentiate suture granuloma from suture recurrence after resection of lung cancer. DWI is more useful than FDG-PET/CT for the differentiation between suture recurrence and suture granuloma after resection for lung cancer.

【 授权许可】

Unknown