Evolution of 2014/15 H3N2 influenza viruses circulating in US: consequences for vaccine effectiveness and possible new pandemic

Frontiers in Microbiology

Matthew eScotch¹  Slobodan ePaessler²  Veljko eVeljkovic³  Vladimir R Perovic³  Sanja eGlisic³  Jelena ePrljic³  Nevena eVeljkovic³ 

[1] Arizona State University;Galveston National Laboratory, University of Texas Medical Branch;Institute of Nuclear Sciences Vinca;

关键词: Influenza Virus;    phylogenetic analysis;    H3N2;    Pandemic potential;    seasonal influenza vaccine effectiveness;   

DOI  :  10.3389/fmicb.2015.01456

来源: DOAJ

【 摘 要 】

A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.

【 授权许可】

Unknown