Pathogenesis, Epidemiology and Variants of Melissococcus plutonius (Ex White), the Causal Agent of European Foulbrood

Journal of Apicultural Science

Pérez-Ordóñez Gerardo¹  Órnelas-Paz José D. J.¹  Zamudio-Flores Paul B.¹  Romo-Chacón Alejandro¹  Rios-Velasco Claudio¹  Acosta-Muñiz Carlos H.¹  de León-Door Adrián Ponce² 

[1] Centro de Investigación en Alimentación y Desarrollo A.C., Unidad Cuauhtémoc, Av. Río Conchos S/N, Parque Industrial. C. P.31570, Apartado Postal 781, Cd. Cuauhtémoc, Chihuahua, Mexico;Universidad Tecnologíca de la Babícora, Km. 1 S/N, Carretera Soto Maynez-Gómez Farías, C. P.31963, Namiquipa, Chihuahua, Mexico;

关键词: apis mellifera;    european foulbrood disease;    melissococcus plutonius;    pathogenesis;    virulence;   

DOI  :  10.2478/jas-2020-0030

来源: DOAJ

【 摘 要 】

The bacterium Melissococcus plutonius is the etiologic agent of the European foulbrood (EFB), one of the most harmful bacterial diseases that causes the larvae of bees to have an intestinal infection. Although EFB has been known for more than a century and is practically present in all countries where beekeeping is practiced, the disease has been little studied compared to American foulbrood. Recently, great advances have been made to understand the disease and the interaction between the pathogen and its host. This review summarizes the research and advances to understand the disease. First, the morphological characteristics of M. plutonius, the infection process and bacterial development in the gut of the larva are described. Also, the epidemiological distribution of EFB and factors that favor the development of the disease as well as the classification of M. plutonius according its genomic and phenotype characteristics are reported. Finally, the new molecular tools for the study of M. plutonius, possible virulence factors in its genome, the issue of current EFB control measures and possible alternatives to the use of antibiotics are addressed.

【 授权许可】

Unknown