Identification and Clinical Application of Immunological Receptors Targeting Mutated Antigens Expressed by Solid Tumors

Cancers

Anna Pasetto¹ 

[1] Department of Laboratory Medicine, Division of Clinical Microbiology, ANA FUTURA, Karolinska Institutet, 14152 Huddinge, Sweden;

关键词: TCR;    CAR;    solid tumors;    mutated antigens;    clinical trials;   

DOI  :  10.3390/cancers12102818

来源: DOAJ

【 摘 要 】

In the recent years, immunotherapy has achieved impressive results utilizing different approaches, from (chimeric antigen receptor) CAR-T cells directed against CD19 for the treatment of leukemia and lymphomas to the Nobel prize-winning strategy of check-point inhibition for the treatment of several solid tumors [...]

【 授权许可】

Unknown