Acute Allergic Reaction due to Milk Proteins Contaminating Lactose Added to Corticosteroid for Injection

Allergology International

Hiromi Shioya¹  Asuka Eda¹  Tetsunori Funabiki¹  Setsuko Ito²  Kazuko Sugai³  Tsutomu Iwata⁴  Asako Fujitsuka⁵ 

[1] Children’s Medical Center, Fujisawa City Hospital;Department of Food Studies and Nutrition, Faculty of Human Life and Science, Doshisha Women’s College of Liberal Arts, Kyoto;National Hospital Organization Yokohama Medical Center;Shimbashi Allergy Rheumatism Clinic, Tokyo, Japan.;Yokohama City University Medical Center, Kanagawa;

关键词: allergic reaction;    cow’s milk allergy;    lactose;    methylprednisolone sodium succinate;    β-lactoglobulin;   

DOI  :  10.2332/allergolint.C-07-59

来源: DOAJ

【 摘 要 】

We encountered two patients with severe cow’s milk allergy who reacted strongly to an injection of methylprednisolone sodium succinate (Sol-Medrol 40 mg® Pfizer, Japan). They came to our hospital because of an asthmatic attack or urticaria and were treated with Sol-Medrol 40 mg®. After the injection, the allergic reaction was immediate. Skin prick tests demonstrated that the β-lactoglobulin contaminating the lactose of the drug preparation caused the immediate allergic reaction.

【 授权许可】

Unknown