HEPATIC TISSUE ENGINEERING (MODERN STATE OF THIS PROBLEM)

Vestnik Transplantologii i Iskusstvennyh Organov

Y.S. Gulay¹  M.Y. Shagidulin²  M.E. Krasheninnikov³  N.A. Onishchenko³ 

[1] M.V. Lomonosov Moscow State University;V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow,Russian FederationI.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation;V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow,Russian Federation;

关键词: liver cells, matrices, tissue-engineering design;   

DOI  :  10.15825/1995-1191-2014-2-103-113

来源: DOAJ

【 摘 要 】

In this article it was discussed the problem of creation implanted hepatic tissue engineering designs as a modern stage of complex investigation for working out bioartifi cial liver support systems. It was determined that for the positive decision of numerous biological and technological problems it is necessary: to use matrices with determined properties, which mimic properties of hepatic extracellular matrix; to use technology for stereotype sowing of these matrices by both parenchymal and non-parenchymal hepatic cells and to improve the technologies for making and assembling of hepatic tissue-engineering designs.

【 授权许可】

Unknown