Study on the Therapeutic Effects of Drug and Cognitive-Behavioral Therapy on Non-Erosive Reflux Disease Patients With Emotional Disorders

Frontiers in Psychiatry

Jing Yang¹  Aimin Leng²  Xiuhua Li³  Yali Zhang³  Kuangming Wu³  Jinwei Liu⁴  Zhenhua Liu⁵  Pandeng Luo⁶  Fengjiao Ding⁶ 

[1] Department of Gastroenterology, The First Affiliated Hospital of University of South China, Hengyang, China;Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, China;Department of Gastroenterology, Yiyang Central Hospital, Yiyang, China;Department of Intensive Care Unit, Yiyang Central Hospital, Yiyang, China;Department of Nephrology, Yiyang Central Hospital, Yiyang, China;Yiyang No.1 Middle School, Yiyang, China;

关键词: non-erosive reflux disease;    cognitive-behavioral therapy;    drug therapy;    anxiety;    depression;   

DOI  :  10.3389/fpsyt.2018.00115

来源: DOAJ

【 摘 要 】

ObjectiveTo assess the correlation between the incidence of non-erosive reflux disease (NERD) and mental and psychological factors, deepen the understanding of the pathogenesis of NERD and explore effective treatments.MethodsNERD patients with mood disorders who met the inclusion criteria were randomly divided into a drug treatment group, a psychotherapy group, and a psychotherapy combined with drug treatment group. Before and after treatment, the patients were retrospectively analyzed using the gastroesophageal reflux disease Questionnaire, Hamilton Depression Scale, Hamilton Anxiety Scale, and SF-36 Quality of Life Scale.ResultsAll three treatments were found to relieve patients’ symptoms and improve their quality of life to some extent. The psychotherapy combined with drug treatment group showed the best overall curative effect. The Hamilton Depression and Anxiety Scale scores were significantly lower in the psychotherapy-alone group and psychotherapy combined with drug treatment group than in the drug treatment alone group at 4, 8, and 12 weeks (P < 0.05).ConclusionMedication, psychotherapy, and psychotherapy combined with medication can relieve clinical symptoms and improve quality of life to varying degrees in patients with NERD.

【 授权许可】

Unknown