Body Composition According to Spinal Cord Injury Level: A Systematic Review and Meta-Analysis

Journal of Clinical Medicine

Lia Bally¹  Taulant Muka²  Marija Glisic²  Peter Francis Raguindin²  Oche Adam Itodo²  Beatrice Minder³  Mirjam Brach⁴  Jivko Stoyanov⁴  Inge Eriks-Hoogland⁴  Ramona Maria Zeh⁴  Gion Fränkl⁴  Simona Capossela⁴  Alessandro Bertolo⁴ 

[1] Department of Diabetes, Endocrinology, Nutritional Medicine, Metabolism, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, 3010 Bern, Switzerland;Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, 3012 Bern, Switzerland;Public Health & Primary Care Library, University Library of Bern, University of Bern, Mittelstrasse 43, 3012 Bern, Switzerland;Swiss Paraplegic Research, Guido A. Zäch Str. 1, 6207 Nottwil, Switzerland;

关键词: spinal cord injury;    paraplegia;    body composition;    fat composition;    obesity;   

DOI  :  10.3390/jcm10173911

来源: DOAJ

【 摘 要 】

The level of injury is linked with biochemical alterations and limitations in physical activity among individuals with spinal cord injury (SCI), which are crucial determinants of body composition. We searched five electronic databases from inception until 22 July 2021. The pooled effect estimates were computed using random-effects models, and heterogeneity was calculated using I² statistics and the chi-squared test. Study quality was assessed using the Newcastle–Ottawa Scale. We pooled 40 studies comprising 4872 individuals with SCI (3991 males, 825 females, and 56 sex-unknown) in addition to chronic SCI (median injury duration 12.3 y, IQR 8.03–14.8). Individuals with tetraplegia had a higher fat percentage (weighted mean difference (WMD) 1.9%, 95% CI 0.6, 3.1) and lower lean mass (WMD −3.0 kg, 95% CI −5.9, −0.2) compared to those with paraplegia. Those with tetraplegia also had higher indicators of central adiposity (WMD, visceral adipose tissue area 0.24 dm² 95% CI 0.05, 0.43 and volume 1.05 L 95% CI 0.14, 1.95), whereas body mass index was lower in individuals with tetraplegia than paraplegia (WMD −0.9 kg/mg², 95% CI −1.4, −0.5). Sex, age, and injury characteristics were observed to be sources of heterogeneity. Thus, individuals with tetraplegia have higher fat composition compared to paraplegia. Anthropometric measures, such as body mass index, may be inaccurate in describing adiposity in SCI individuals.

【 授权许可】

Unknown