Coupling between fast and slow oscillator circuits in Cancer borealis is temperature-compensated

eLife

Daniel Powell¹  Sara A Haddad¹  Eve Marder¹  Srinivas Gorur-Shandilya¹ 

[1] Biology Department and Volen Center, Brandeis University, Waltham, United States;

关键词: crabs;    pyloric rhythm;    gastric mill rhythm;    stomatogastric ganglion;    Cancer borealis;   

DOI  :  10.7554/eLife.60454

来源: DOAJ

【 摘 要 】

Coupled oscillatory circuits are ubiquitous in nervous systems. Given that most biological processes are temperature-sensitive, it is remarkable that the neuronal circuits of poikilothermic animals can maintain coupling across a wide range of temperatures. Within the stomatogastric ganglion (STG) of the crab, Cancer borealis, the fast pyloric rhythm (~1 Hz) and the slow gastric mill rhythm (~0.1 Hz) are precisely coordinated at ~11°C such that there is an integer number of pyloric cycles per gastric mill cycle (integer coupling). Upon increasing temperature from 7°C to 23°C, both oscillators showed similar temperature-dependent increases in cycle frequency, and integer coupling between the circuits was conserved. Thus, although both rhythms show temperature-dependent changes in rhythm frequency, the processes that couple these circuits maintain their coordination over a wide range of temperatures. Such robustness to temperature changes could be part of a toolbox of processes that enables neural circuits to maintain function despite global perturbations.

【 授权许可】

Unknown