A case report: anti-NMDA receptor encephalitis

Journal of Community Hospital Internal Medicine Perspectives

Pavan Bhat¹  Preetam Jolepalem¹  Charmian Sittambalam¹  Ameer Ahmed¹ 

[1] MedStar Franklin Square Medical Center;

关键词: Ovarian;    teratoma;    anti-NMDAR;    encephalitis;    frontotemporal;    hippocampal;   

DOI  :  10.1080/20009666.2018.1481326

来源: DOAJ

【 摘 要 】

N-methyl-d-aspartate receptor (NMDAR) antibody encephalitis is a potentially fatal autoimmune syndrome in which there is antibody production against the NMDAR causing profound dysregulation of neurotransmission. The syndrome is frequently associated with ovarian teratomas and women are disproportionately affected. Patients most often present with a constellation of neuropsychiatric signs and symptoms, including memory loss, hallucinations, and decreased level of consciousness. This condition is lethal if left untreated. Immunotherapy and surgical resection of the culprit malignancy often results in the rapid resolution of symptoms.

【 授权许可】

Unknown