A Good Death? Report of the Second Newcastle Meeting on Laboratory Animal Euthanasia

Animals

Daniel M. Weary¹  I. Joanna Makowska¹  Ngaire Dennison²  Nicole Marquardt³  Craig Johnson⁴  Larry Carbone⁵  Mark J. Prescott⁶  Penny Hawkins⁷  Gareth Readman⁸  Huw D. R. Golledge⁹ 

[1] Animal Welfare Program, University of British Colombia, 2357 Main Mall, Vancouver, BC V6T 1Z4, Canada;Animals in Science Regulation Unit, Home Office Science, 1st Floor Peel NE, 2 Marsham Street, London SW1P 4DF, UK;Institute of Pharmacology and Toxicology, Freie Universität Berlin, Koserstraße 20, Berlin 14195, Germany;Institute of Veterinary, Animal and Biomedical Sciences, Private Bag 11 222, Massey University, Palmerston North 4442, New Zealand;Laboratory Animal Resource Center, University of California, San Francisco, CA 94143, USA;National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), Gibbs Building, 215 Euston Road, London NW1 2BE, UK;Research Animals Department, Royal Society for the Prevention of Cruelty to Animals (RSPCA), Wilberforce Way, Southwater, Horsham, West Sussex RH13 9RS, UK;School of Biology, University of Plymouth, Smeaton 008D, Drakes Circus, Plymouth PL4 8AA, UK;Universities Federation for Animal Welfare (UFAW), The Old School, Brewhouse Hill, Wheathampstead, Hertfordshire AL4 8AN, UK;

关键词: animal welfare;    carbon dioxide;    euthanasia;    humane killing;    mouse;    rat;    refinement;    3Rs;    zebrafish;   

DOI  :  10.3390/ani6090050

来源: DOAJ

【 摘 要 】

Millions of laboratory animals are killed each year worldwide. There is an ethical, and in many countries also a legal, imperative to ensure those deaths cause minimal suffering. However, there is a lack of consensus regarding what methods of killing are humane for many species and stages of development. In 2013, an international group of researchers and stakeholders met at Newcastle University, United Kingdom to discuss the latest research and which methods could currently be considered most humane for the most commonly used laboratory species (mice, rats and zebrafish). They also discussed factors to consider when making decisions about appropriate techniques for particular species and projects, and priorities for further research. This report summarises the research findings and discussions, with recommendations to help inform good practice for humane killing.

【 授权许可】

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