Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era

Frontiers in Immunology

Xingguang Lin¹  Renjie Wang¹  Di Wu¹  Rui Long¹  Dongrui Deng¹  Dan Lv¹  Shujie Liao¹  Mengzhou He²  Jing Peng²  Yun Zhao² 

[1] Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;

关键词: immunopathogenesis;    SARS-CoV-2;    COVID-19;    pregnant;    vaccine;   

DOI  :  10.3389/fimmu.2021.683440

来源: DOAJ

【 摘 要 】

Since December 2019, Wuhan, China, has experienced an outbreak of coronavirus disease (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pregnant women are deductively considered to be in immunosuppressive condition for the safety of semi-allograft fetuses, which increases the risk of being infected by the virus. In this review, we analyzed the unique immunological characteristics of pregnant women and reviewed their known outcomes at different trimesters from the perspective of underlying mechanisms that have been studied and speculated so far.

【 授权许可】

Unknown