Sulfolobus – A Potential Key Organism in Future Biotechnology

Frontiers in Microbiology

Bettina Siebers¹  Lu Shen¹  Sonja-Verena Albers²  Julian Quehenberger³  Oliver Spadiut³ 

[1] Department of Molecular Enzyme Technology and Biochemistry, Faculty of Chemistry – Biofilm Centre, University of Duisburg-Essen, Essen, Germany;Molecular Biology of Archaea, Institute of Biology II-Microbiology, Faculty of Biology, University of Freiburg, Freiburg im Breisgau, Germany;Research Division Biochemical Engineering, Faculty of Technical Chemistry, Institute of Chemical, Environmental and Biological Engineering, Vienna University of Technology, Vienna, Austria;

关键词: Sulfolobus;    biotechnology;    thermophile;    acidophile;    bioprocessing;    biorefinery;   

DOI  :  10.3389/fmicb.2017.02474

来源: DOAJ

【 摘 要 】

Extremophilic organisms represent a potentially valuable resource for the development of novel bioprocesses. They can act as a source for stable enzymes and unique biomaterials. Extremophiles are capable of carrying out microbial processes and biotransformations under extremely hostile conditions. Extreme thermoacidophilic members of the well-characterized genus Sulfolobus are outstanding in their ability to thrive at both high temperatures and low pH. This review gives an overview of the biological system Sulfolobus including its central carbon metabolism and the development of tools for its genetic manipulation. We highlight findings of commercial relevance and focus on potential industrial applications. Finally, the current state of bioreactor cultivations is summarized and we discuss the use of Sulfolobus species in biorefinery applications.

【 授权许可】

Unknown