New Glycosides from the Fruits of Nicandra physaloides

Molecules

Yan Liu¹  Bing-You Yang¹  Zhen-Peng Xu¹  Hong-Wei Guo¹  Yan-Gang Cheng¹  Shao-Wa Lv¹  Hai-Xue Kuang¹  Hai-Bing Jiang¹ 

[1] Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China;

关键词: Nicandra physaloides;    phenyl-glycosides;    fat glycosides;    RAW 264.7;    inflammation;   

DOI  :  10.3390/molecules22050828

来源: DOAJ

【 摘 要 】

Three new glycosides (1–3) and 15 known ones (4–18) were isolated and identified from the fruits of Nicandra physaloides. The structures of these compounds were established by 1D and 2D NMR spectra and HR-ESI-MS. The compounds (4–18) were the first time isolated from the Nicandra genus and they (except 8, 10, 14) exhibited inhibitions on the NO release of LPS-induced RAW 264.7 cells with IC50 values from 26.9 to 47.5 μM.

【 授权许可】

Unknown