Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer

Shuyang YAO¹  Yi ZHANG¹ 

[1] Department of Thoracic Surgery, Xuanwu Hospital, Diagnostic and Treatment Centers of Lung Cancer, Capital Medical University, Beijing 100053, China;

关键词: lung neoplasms;    local advanced stage;    neoadjuvant therapy;    immunotherapy;   

DOI  :  10.3779/j.issn.1009-3419.2020.01.09

来源: DOAJ

【 摘 要 】

Immune checkpoint inhibitor (ICI) has been proven to be a major breakthrough in patients with advanced non-small cell lung cancer. Up to now, neoadjuvant therapy using ICI are rare. However, in the context of cancer immunotherapy, neoadjuvant treatment may offer an extra advantage. In this review, we will disscuss the existing preclinical data and emerging clinical findings in the neoadjuvant setting and its potential mechanism of action. We will also highlight the potential damage and the questions that are required to be answered.

【 授权许可】

Unknown