Basic mechanisms of iron metabolism regulation and their clinical significance

Onkogematologiâ

L. M. Meshсheryakova¹  T. V. Sokolova²  A. A. Levina²  M. M. Tsybulskaya² 

[1] Hematologic Scientific Center, Ministry of Health of Russia, Moscow;Outpatient center “City polyclinic № 62”, Moscow Department of Health Care;

关键词: anemia;    diagnostics;    pathogenesis;   

DOI  :  10.17650/1818-8346-2014-9-3-67-71

来源: DOAJ

【 摘 要 】

This article is а composition of literature and experimental data of iron metabolism. There were studied the level of DMT-1, ferroportin, hepcidin at different stages of anemia and hemochromatosis. It is clear that the level of DMT-1 regulates by the hepcidin. Increaseing of the hepcidin concentration and decreasing DMT-1 level in patients with hemochromatosis explained good results of treatment.

【 授权许可】

Unknown