Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation

Applied Sciences

Michael Pircher¹  Bernhard Baumann¹  ChristophK. Hitzenberger¹  Florian Beer¹  RahulP. Patil²  Abhijit Sinha-Roy² 

[1] Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090 Vienna, Austria;Narayana Nethralaya Foundation, Bengaluru 560099, India;

关键词: cornea;    optical coherence tomography;    polarization sensitive imaging;    dispersion compensation;    ultra-high resolution;   

DOI  :  10.3390/app9204245

来源: DOAJ

【 摘 要 】

Noninvasive corneal imaging is essential for the diagnosis and treatment control of various diseases affecting the anterior segment of the eye. This study presents an ultrahigh resolution polarization sensitive optical coherence tomography instrument operating in the 840 nm wavelength band that incorporates a conical scanning design for large field of view imaging of the cornea. As the conical scanning introduces a dispersion mismatch depending on the scanning angle, this study implemented variable, location dependent, numerical dispersion compensation in order to achieve high axial resolution throughout the imaged volume. The corneal images were recorded in vivo in healthy volunteers showing various details of corneal structures.

【 授权许可】

Unknown