Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation

Endocrinology and Metabolism

Min Kyoung Lee¹  Young Jun Choi¹  Jeong Hyun Lee¹  Jung Hwan Baek¹  Sae Rom Chung¹  Yu-Mi Lee²  Tae Yong Kim³ 

[1] Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea;Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea;Division of Endocrinology & Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea;

关键词: thyroid nodule;    radiofrequency ablation;    ultrasonography;   

DOI  :  10.3803/EnM.2020.35.2.407

来源: DOAJ

【 摘 要 】

Background Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose in water (5% DW) can reduce nerve damage during RFA. This study validated the efficacy of injecting cold 5% DW for management of nerve damage during RFA. Methods Between November 2017 and December 2018, 242 patients underwent 291 RFA sessions for treatment of benign thyroid nodules or recurrent thyroid cancers. Using a standardized technique, cold (0°C to 4°C) 5% DW was immediately injected around the damaged nerve into patients with any symptoms suggesting nerve damage. The incidence of nerve damage, the volume of 5% DW injected, symptom recovery time and the incidence of permanent nerve damage were evaluated. Results Nineteen patients experienced nerve damage symptoms related to 21 RFA sessions, including 17 patients during 19 sessions and two patients on the day after two sessions. Patients with nerve damage symptoms detected during RFA were treated by injection of a mean 41 mL (range, 3 to 260) cold 5% DW, but the two patients who experienced symptoms the next day did not receive cold 5% DW injections. Immediate recovery was observed after 15 RFA sessions in 14 patients. No patient experienced permanent nerve damage. Conclusion Injection of cold 5% DW is effective in managing nerve damage during RFA of thyroid lesions.

【 授权许可】

Unknown