Cutaneous Leishmaniasis with Mucosal Involvement

Türkiye Parazitoloji Dergisi

Ebru Çelik¹  Tayibe Bal²  Mehmet Çabalak²  Tuğba Kaya³  Gülnaz Çulha³ 

[1] Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi, Deri ve Zührevi Hastalıkları Anabilim Dalı, Hatay, Türkiye;Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Hatay, Türkiye;Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi, Parazitoloji Anabilim Dalı, Hatay, Türkiye;

关键词: leishmaniasis;    leishmania tropica;    treatment;   

DOI  :  10.4274/tpd.galenos.2021.21931

来源: DOAJ

【 摘 要 】

Leishmaniasis is a protozoan parasitic disease transmitted to humans by infected female sand flies. Turkey has received more than three million immigrants from Syria because of the civil war and political instability. This study reported cases of two patients, who were from Syria and lived in Hatay, with cutaneous leishmaniasis and mucosal involvement. Two patients presented to the infectious diseases clinic with a complaint of facial lesions and were subsequently referred to the parasitology department laboratory. Smears were prepared from the lesions, stained with Giemsa and examined under a microscope. Moreover, aspirates taken from the patients’ lesions were inoculated into the modified Novy-MacNeal-Nicolle medium. The diagnosis was made when amastigotes were detected in both smears. Proliferation of promastigotes was observed in one of the clinical specimens inoculated on the medium. By PZR-RFLP, Leishmania tropica were detected in the isolate. Both patients were treated with amphotericin B. One patient was treated again with a pentavalent antimony compound because of the recurrence of the lesion.

【 授权许可】

Unknown