Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporated with Silver Nanoclusters via Green Tea Extract for Antibacterial Applications

Designed Monomers and Polymers

Kehui Hu¹  Yi Sun²  Constantinus Politis²  Amin Shavandi³  Tianwen Wang⁴  Lei Nie⁴  Rui Zhao⁴  Fang Zhang⁴  Can Wang⁴ 

[1] Tsinghua University;University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven;Université Libre De Bruxelles;Xinyang Normal University;

关键词: silver nanoparticles;    antibacterial hydrogel;    green synthesis;    reductive metabolites;    tea extract;   

DOI  :  10.1080/15685551.2020.1804183

来源: DOAJ

【 摘 要 】

Silver-based nanoparticles and biomaterials have extensive biomedical applications owing to their unique antimicrobial properties. Thus, green and facile synthesis of such materials is highly desirable. This study reports an antibacterial hydrogel based on polyvinyl alcohol/sodium alginate network with the incorporation of silver nanoparticles (AgNPs), which is greenly synthesized by reductive metabolites obtained from the leaves of green tea. The ‘flower-shape’ AgNPs were acquired, it formed a mono-disperse system with a distinct uniform interparticle separation. The average size of AgNPs varied from 129.5 to 243.6 nm, which could be regulated by using different volumes of the green tea extract. Zeta potentials of the AgNPs were from −39.3 mV to −20.3 mV, indicating the moderate stability of the particles in water. In the next stage, the antibacterial polyvinyl alcohol/sodium alginate hydrogels were fabricated by incorporating prepared AgNPs. Scanning Electron Microscopy (SEM) images showed that the porous structure was obtained, and Energy Dispersive X-Ray (EDX) analysis confirmed that the AgNPs were uniformly dispersed in the polymer network. The hydrogels exhibited superior water absorption properties, which were characterized by a high swelling ratio (500–900%) and fast equilibrium. The hydrogels also exhibited good antimicrobial activity in assays with Gram-positive bacteria Escherichia coli and Gram-negative bacteria Staphylococcus aureus. To sum up, a process for the green preparation of antibacterial hydrogels based on AgNPs derived from tea leaves as a conveniently available cheap local agricultural product was established.

【 授权许可】

Unknown