Recognition of Chiral Carboxylates by Synthetic Receptors

Molecules

Patryk Niedbała¹  Sylwia Wasiłek¹  Kajetan Dąbrowa¹  Janusz Jurczak¹ 

[1] Institute of Organic Chemistry, Polish Academy of Sciences (PAS), 01-224 Warsaw, Poland;

关键词: supramolecular chemistry;    anion recognition;    chiral recognition;    carboxylates;    synthetic receptors;   

DOI  :  10.3390/molecules26216417

来源: DOAJ

【 摘 要 】

Recognition of anionic species plays a fundamental role in many essential chemical, biological, and environmental processes. Numerous monographs and review papers on molecular recognition of anions by synthetic receptors reflect the continuing and growing interest in this area of supramolecular chemistry. However, despite the enormous progress made over the last 20 years in the design of these molecules, the design of receptors for chiral anions is much less developed. Chiral recognition is one of the most subtle types of selectivity, and it requires very precise spatial organization of the receptor framework. At the same time, this phenomenon commonly occurs in many processes present in nature, often being their fundamental step. For these reasons, research directed toward understanding the chiral anion recognition phenomenon may lead to the identification of structural patterns that enable increasingly efficient receptor design. In this review, we present the recent progress made in the area of synthetic receptors for biologically relevant chiral carboxylates.

【 授权许可】

Unknown