Cytochemical and immunocytochemical characteristics of Meckel's diverticulum with heterotopic rests of pancreatic tissue

Vojnosanitetski Pregled

关键词: Meckel diverticulum;    diagnostic tecniques;    digestive system;    histocytochemistry;    immunohistochemistry;    pancreas;    choristoma;   

DOI  :  10.2298/VSP1012021P

来源: DOAJ

【 摘 要 】

Background. Meckel’s diverticulum (MD) is a congenital anomaly of the smallintestine. It results from incomplete obliteration and resorption of theproximal omphaloenteric duct connecting yolk sac with primitive gut in thefetal period. Case report. A case of 20-year old female with ectopicpancreatic rests in a MD was reported. She was hospitalized with clinicalsigns of acute appendicitis. During surgery an inflamated Meckel’sdiverticulum was found and a clinoid resection of the diverticulum wasperformed. Histologic examination revealed pancreatic tissue in the removeddiverticulum. Endocrine cells (EC) were detected with Masson staining andaberrant pancreatic tissue with immunocytochemical LSAB2 method using pancytokeratin as epithelial marker. Conclusion. Most of MD are asymptomatic andaccessory finding during laparothomias for different causes, butcomplications of undiagnozed MD can be serious (diverticulitis, perforationwith peritonitis or intestinal obstruction caused by invagination). Inunclear cases, additional cytochemical and immunocytochemical diagnosticscould be done.

【 授权许可】

Unknown