Capillary blood reference intervals for platelet parameters in healthy full-term neonates in China

BMC Pediatrics

Guo Li¹  Chi Zhang¹  Jiubo Fan²  Ling Feng³  Yanli Huang⁴  Dongyan Cui⁵  Qun Hu⁵  Yan Hou⁶ 

[1] Department of Clinical Laboratory, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;Department of Clinical Laboratory, Xiangyang Central Hospital;Department of Gynaecology and Obstetrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;Department of Gynaecology and Obstetrics, Xiangyang Central Hospital;Department of Paediatric Haematology and Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;Department of Paediatrics, Xiangyang Central Hospital;

关键词: Neonates;    Capillary blood;    Platelet count;    Platelet parameters;    Reference intervals;   

DOI  :  10.1186/s12887-020-02373-6

来源: DOAJ

【 摘 要 】

Abstract Background No consensus has been reached on capillary blood reference intervals for platelet parameters in full-term neonates. We aimed to establish neonatal capillary blood reference intervals for platelet parameters and evaluate influences of sex, gestational age and postnatal age on platelet parameters. Methods This study was a prospective investigation and implemented in 594 healthy full-term neonates from 12 to 84 h of age, using SYSMEX XN-9000 haematology automatic analyser by means of capillary blood. Reference intervals for platelet parameters were defined by an interval of 2.5th − 97.5th percentiles. Results Capillary reference interval for platelet count was (152–464) × 109/L. No significance was found between sex-divided reference intervals for platelet parameters. The values of platelet count changed minimally across gestational age (37–41 weeks) and postnatal age (12–84 h). Reference intervals for other platelet parameters were affected by these factors to a different extent. Conclusions We established capillary blood reference intervals for platelet parameters in the first days after birth of full-term neonates in China.

【 授权许可】

Unknown