Autologous stem-cell transplantation for multiple myeloma: a Brazilian institution experience in 15 years of follow-up

Einstein (São Paulo)

关键词: Multiple myeloma;    Transplantation;    autologous;    Bone marrow transplantation;    Survivorship (Publich Health);   

DOI  :  

来源: DOAJ

【 摘 要 】

Objective: To determine the 5-year post-transplant survival ofpatients with multiple myeloma. Methods: A retrospective study inpatients diagnosed with multiple myeloma submitted to autologousbone marrow transplantation at a Brazilian institution, during theperiod of 1993 to 2007. Results: Seventy-three patients wereevaluated with a median age of 55 years. Survival in 5 years was75% (2.4 to 60 months). Statistical analysis demonstrated statisticalsignificance for the applied grade of response prior to treatment withautologous bone marrow transplantation (p = 0.01). There was nostatistical significance for clinical staging or time of diagnosis (before or after the year 2000). Conclusion: Experience in autologous bone marrow transplantation for multiple myeloma at a Brazilian institution demonstrated an evolution consistent with that of medical literature and highlighted the importance of a response to treatment prior to transplantation in the survival of these patients.

【 授权许可】

Unknown