期刊论文详细信息
Emerging Infectious Diseases | |
Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010 | |
关键词: caspofungin; echinocandins; FKS mutation; Candida albicans; Candida glabrata; Candida krusei; | |
DOI : 10.3201/eid1801.110556 | |
来源: DOAJ |
【 摘 要 】
We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.
【 授权许可】
Unknown