Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010

Emerging Infectious Diseases

关键词: caspofungin;    echinocandins;    FKS mutation;    Candida albicans;    Candida glabrata;    Candida krusei;   

DOI  :  10.3201/eid1801.110556

来源: DOAJ

【 摘 要 】

We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.

【 授权许可】

Unknown