Smaller Cortisol Awakening Responses Are Associated with Greater Visual Dependence in Postural Control

Healthcare

Monica Milani¹  Phil Evans¹  John F. Golding¹  Angela Clow¹  Nina Smyth¹  Lisa Thorn¹  Maria Flynn¹ 

[1] School of Social Sciences, Psychology, University of Westminster, 115 New Cavendish Street, London W1W 6UW, UK;

关键词: salivary cortisol;    cortisol awakening response;    hypothalamic–pituitary–adrenal (HPA) axis;    postural control;    visual dependency;   

DOI  :  10.3390/healthcare9060723

来源: DOAJ

【 摘 要 】

There are known links between the hypothalamic–pituitary–adrenal (HPA) axis and systems responsible for regulating posture. Our aim was to explore directly, for the first time, whether an aspect of circadian HPA axis activity (the cortisol awakening response: CAR) was associated with greater visual dependency in postural control. For measurement of the CAR, electronically monitored saliva samples were collected by participants following morning awakening in their home environment. On the afternoons of the same days, postural sway was measured in the laboratory by exposing participants to static (control) and moving visual stimuli whilst standing still and upright on a force platform. Visual dependence was assessed as the increase in postural sway (path length) during exposure to the moving compared with the static condition. The 44 measurement days were derived from four days for each of eleven healthy participants (mean ± SD age: 51.18 ± 3.3 years). As expected, postural sway was greater when exposed to moving versus static cues. Mixed regression modelling showed that participants with smaller four day average CARs had greater deterioration in postural sway when presented with moving stimuli. These data are the first to document associations between the CAR and visual dependency in postural sway.

【 授权许可】

Unknown